Defensive backs and linebackers were the most-targeted positions, with 34 defensive backs and 33 linebackers selected. Notre Dame had 10 players drafted, four more than any other school.
Ohio State defensive tackle Dan Wilkinson was the No. 1 overall pick by the Bengals. It was the third time in four years that the No. 1 pick was a defensive tackle. Prior to that, a defensive tackle hadn't been selected No. 1 since Kenneth Sims, by the Patriots in 1982.
San Diego State running back Marshall Faulk was selected second by the Colts. Faulk, who was second-team All-Pro as a rookie, ended the 2008 season ranked seventh in career rushing touchdowns with 100. He was the Offensive Rookie of the Year. Ole Miss defensive tackle Tim Bowens, selected 20th by the Dolphins, was the Defensive Rookie of the Year.
Among the notable late-round selections was Utah running back Jamal Anderson, drafted 201st overall (7th round) by the Falcons. Anderson had four seasons with 1,000+ rushing yards, including 1,846 in 1998.
Kentucky linebacker Marty Moore was Mr. Irrelevant, the 222nd and final selection of the draft, by the New England Patriots. Moore started 20 games in his eight-year NFL career, including four as a rookie with the Patriots.