The Kansas City Chiefs held the third overall selection in the 2009 NFL Draft, marking the team's second consecutive year with a top-5 selection. With the third overall pick, the Chiefs selected DE Tyson Jackson from LSU.

In the 2008 season, the Chiefs finished 2-14 in the regular season, finishing in last place in the AFC West. This will be the Chiefs first draft under new head coach Todd Haley, who was hired to replace Herm Edwards in February.

The Chiefs have selected in the Top 5 seven times in team history, and have selected a defensive player each time.
- The Chiefs acquired the 237th overall pick (7th round) from the Miami Dolphins in exchange for a 7th-round pick in 2010 on April 26, 2009.

- The Chiefs traded the 2nd pick in the 2nd round (34th overall) to the New England Patriots in exchange for Matt Cassel and Mike Vrabel on Feb. 28, 2009.