In 2006, Moala made 10 starts at nose tackle and defensive tackle, and played 13 games. He finished with 20 total tackles and was an honorable mention All-Pac-10 selection.
Moala made 33 total tackles as a junior, again earning honorable mention All-Pac-10 honors while playing alongside first-round pick Sedrick Ellis.
With Ellis gone to the NFL in 2008, Moala was the focal point of the Trojans defensie line. He finished the season with 30 total tackles (10.0 for loss) and 4.5 sacks. He also blocked two field goals, both coming against Arizona State. Moala was a first team All-Pac 10 selection and earned third team All-America honors from The Associated Press.
Moala played 10 games as a rookie for the Colts, including a start in the season finale against the Bills. He finished the 2009 regular season with seven total tackles. He was innactive for both of the Colts playoff games leading up to Super Bowl XLIV.